Stem cell and PRP treatments seek to cure the cause of chronic musculoskeletal pain by reversing damage and degeneration of connective tissue caused by traumatic injury, repetitive motion injury, arthritis and the aging process. By administering stem cells and natural substances with growth factors  directly into a problem area, we can regenerate normal tissue, eliminate dysfunction and pain, and restore health.

Damaged and degenerated ligaments, tendons, muscles, and joint surfaces cause pain and dysfunction. Damaged and degenerated connective tissues have decreased blood flow, entrapped nerve ending, and accumulation of metabolic waste. The goal of prolotherapy, using stem cells and platelet rich plasma (PRP)  is to restore health to these compromised tissues. Restoration of health to these tissues decreases or can eliminate pain and normalize function.

 Regenerative Injection Therapies have a success rate of over 85%.

Regenerative Medicine

Regenerative Medicine

An effective therapy for chronic and acute conditions such as old injuries, joint pains and arthritis.

Platelet Rich Plasma

Platelet Rich Plasma

Use your body’s own natural growth factors to heal and regenerate your tissues.

Stem Cells

Stem Cells

Advances in scientific research allow us to utilize stem cells and support regeneration of tissue.

Prolotherapy, PRP & Stem Cells


Prolotherapy, also known as Regenerative Injection Therapy (RIT), is the injection of natural substances directly into damaged musculoskeletal tissues in order to trigger the production of growth factors. This launches a controlled inflammation that stimulates the body’s natural healing mechanisms to lay down new, strong collagen fibers and cells.
We can use dextrose, Platelet Rich Plasma (PRP), and stem cell treatments to achieve optimal healing.
The previously damaged tissue goes through the same healing cascade as when first injured and is given a second chance to heal. Studies have been performed showing microscopic views of tendons before and after RIT and show that RIT does in fact normalize tissue. RIT is extremely safe, relatively inexpensive, and compared to chronic pain is relatively painless. Treatments are given at three to six week intervals and depending on the severity of the condition.
Prolotherapy is a nonsurgical treatment that relieves musculoskeletal pain by strengthening and tightening ligaments and tendons around affected joints. Ligaments and tendons are tough, fibrous bands of tissue that connect bone to bone and bone to muscle. As long as they are strong and taut, they keep joints stable and properly aligned, allowing for smooth, pain-free movement. When they become injured, weak, or lax, the resulting misalignment impinges on nerves and blood vessels and causes pain. Lasting relief can be obtained by restoring the integrity of these supporting structures, returning things to their proper positions and taking pressure off sensitive tissues.
This therapy, which requires special training that a few conventional physicians have undertaken, involves injections of a natural solution into the painful area. This triggers the body’s natural healing response and promotes the proliferation of new collagen, which is the building block of ligaments and tendons. As these structures become thicker and stronger, pain subsides, range of motion returns, and cartilage degeneration slows down.
Many of the patients treated with prolotherapy have noted significant relief after a single treatment. Sometimes it usually takes several sessions to achieve lasting pain relief and a return to normal function.
When this therapy is combined with other components of our multi-faceted pain relief program, patients can expect exceptional results.


Platelet-rich plasma (PRP) is a powerful therapy that relieves pain and facilitates recovery from all types of acute and chronic injuries, such as sprains, strains, arthritis, and degenerative joint disease. PRP harnesses the healing power of platelets—components in the blood that initiate and regulate tissue repair—by delivering concentrations of the body’s own platelets directly to damaged or degenerated areas.
PRP treatment at Encinitas Prolotherapy involves removing a vial of a patient’s own blood and spinning it in a centrifuge to separate out the red blood cells, plasma, and other components. This produces a very small amount of concentrated platelets in a little plasma (the golden/clear, liquid part of blood). The patient’s PRP is then placed in a syringe and injected into the affected area, which is numbed beforehand to make the injection more comfortable. A single injection to each site is all that is usually needed, although some patients require more, spaced out over time.
Over the next few weeks, the regeneration process that PRP turns on becomes evident, with often dramatic improvements in pain, range of motion, function, and quality of life.
Platelets are nature’s reservoirs of proteins, peptides, and other compounds that facilitate healing. They include clotting factors to stop bleeding; inflammatory chemicals to drive the acute phase of the healing process; and growth factors to promote tissue regeneration and the formation of blood vessels that nourish new tissues. PRP treatment simply directs and amplifies the natural healing process.
Elite athletes have been benefiting from this therapy for years, and surgeons have been using PRP to speed healing of bones, surgical incisions, and more. However, PRP’s greatest use may be to help relieve pain and restore function in areas affected by degenerative joint disease. This therapy is an excellent treatment for chronic pain and often delivers results after other interventions have failed. It is also useful for patients suffering with age-related arthritis and may help stave off hip and knee replacement and spinal surgery.
Best of all, because PRP is an “autologous” procedure, meaning it’s derived or transferred from the patient’s own body, it’s exceptionally safe. It’s also minimally invasive, well-tolerated, and requires little to no recovery time. Finally, it costs a fraction of the price of any surgical procedure.
Because platelet-rich plasma turns on the body’s natural healing mechanisms, it is an effective therapy for a broad range of acute and chronic disorders. Various PRP preparations have been used to enhance the healing of bones, cartilage, tendons, ligaments, and surgical wounds, and it’s been enthusiastically adopted by orthopedic, plastic, periodontal, and maxillofacial surgeons.


Stem cells are “master cells” which have the ability to replace any sick, damaged or worn out cells – they can become virtually any type of cell in your body – heart cells, liver cells, pancreatic cells, muscle cells, brain cells, and even the cells in the eyes, the joints and more. Serving as a regeneration system, they divide without limit and travel throughout your body to support optical organ and tissue renewal.
There is nothing magical or mysterious about how stem cells work. Stem cells can help repair or regenerate damaged tissue; it is human physiology. When you think about it, from the viewpoint that stem cells are the body’s natural repair system throughout life, it becomes normal to think that these cells could help a variety of conditions and improve a person’s overall health.
As you age, the number and quality of stem cells that circulate in your body gradually decrease, leaving your body more susceptible to injury and other age-related health challenges. Just as antioxidants are important to protect your cells from “free radical” damage, stem cells are equally important in maintaining proper functioning in your body.


  • Osteo-Arthritis

  • Joint Pain (from any cause except cancer)

  • Neck Pain/Headaches (except true hormonal headaches or fibromyalgia syndrome with no history of trauma)

  • Sports Injuries (such as tendonitis/tendonosis, rotator cuff tear, ACL tear, torn meniscus, chronic ankle sprains, chronic shoulder dislocations, Achilles tendonosis, etc)

  • Overuse Injuries (plantar fasciitis, carpal tunnel syndrome, texters/quilters thumb, chondromalacia patellae, etc)

  • Bone spurs


  • Cancer Pain

  • Fibromyalgia Syndrome with no history of trauma


In the healthy human system, we are capable of healing following an injury. Damage to musculoskeletal structures triggers a critically important inflammatory pathway followed by a healing cascade. Anti-inflammatory drugs such as ibuprofen suppress this healing cascade. The majority of healing occurs in the first eight weeks after an injury. During this time the body produces growth factors and recruits stem cells in order to stimulate growth of new tissue. After this time, if healing is not complete there is a localized decrease blood flow, entrapment of nerve endings, and accumulation of metabolic waste. In essence, these tissues turn from normal connective tissue into scar tissue. As a direct result, nerve receptors in these tissues chronically fire pain signals. Sub-optimal healing leads to structures that do not have sufficient tensile strength (lax ligaments or joint capsules). Stretched ligaments are no longer able to stabilize their corresponding joint. This leads to muscle spasm in an attempt to stabilize joints and arthritis. Arthritis, similarly, is degeneration of joint surface tissue secondary to macro or micro trauma.

Most chronic musculoskeletal pain conditions are due to degenerative processes, not inflammatory processes. Most back and neck pain is due to damaged, degenerated tissues, not herniated discs even if herniated discs are present.

Conventional treatment of musculoskeletal pain conditions involves palliative drug therapies until the condition becomes bad enough to warrant surgery. Arthroscopic surgery for arthritis has been definitively proven to not be effective long-term. Statistics for disc surgery for back/neck pain are dismal.

Alternative modalities such as chiropractic, massage, and acupuncture frequently can sometimes be curative for mild to moderate conditions, but often only provide short term relief for advanced cases.

Patients who are not good candidates for surgery and for whom alternative medicine has not been effective are often experience the best outcomes with Regenerative Pain Medicine.

At Encinitas Prolotherapy, our principle interventions are prolotherapy, platelet rich plasma and stem cell science. We use the principles of Naturopathic Medicine and Functional Medicine to maximize healing.  The goal of Prolotherapy, PRP, and Regenerative Medicine is to support the body’s innate healing abilities to cure the cause of pain.